Advanced understanding of Staphylococcus aureus and Pseudomonas aeruginosa Infections in EuRopE – Intensive Care Units (ASPIRE-ICU) is a prospective, observational, multicenter, epidemiological cohort study. Nested within routine surveillance among ICU patients in Europe. Aimed at the advanced understanding of Staphylococcus aureus and Pseudomonas aeruginosa infections in Europe (ASPIRE).
Predicting risk of infection during ICU stay
The goal is to estimate the incidence of S. aureus and P. aeruginosa ICU pneumonia, especially ventilator-associated pneumonia (VAP). Another goal is to assess its association with patient-related and contextual factors. For example comorbidities, colonization status, and relevant biomarkers. With this information, a risk prediction model will be developed to quantify the risk of acquiring S. aureus or P. aeruginosa pneumonia during ICU stay.
Study team members
Scientist / EFPIA Co-lead / MedImmune
LAB-Net Representative / Laboratory manager / University of Antwerp
Investigator / Academic / University Medical Center Utrecht
Study level information
- Study NO NCT02413242
- Study Name ASPIRE-ICU
- Study Type Observational
- Study Status Recruitment Complete
- Enrollment Period 05/15 - 05/18
- Total subjects planned 2000
- Total subjects screened 9561
- Total subjects enrolled 2006
- Total subjects completed 1998
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- Preparation phase
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- Trial period
Country level information
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